- About Non-Small Cell Lung Cancer
- About XALKORI
- Testing for ALK
- Patient Resources
Resources & tools
If you’d like more information about XALKORI® (crizotinib), lung cancer, biomarker–driven therapy, or the ALK fusion gene, you may want to start with the following downloads and links.
Helpful downloads for you and everyone helping with your fight
Download and print these useful resources. They’ll help educate you about lung cancer, ALK testing, and XALKORI, and prepare you for what to expect.
Doctor Discussion Guide
You may have questions for your doctor about XALKORI and ALK testing. This useful discussion guide lets you pick from a menu of questions, and come up with your own.
Welcome to XALKORI
If your doctor has prescribed XALKORI for you, there are some things you should know before starting it. We’ll take you through the information you need to know before you start treatment with XALKORI.
Filling your XALKORI prescription
XALKORI is available at certain specialty pharmacies. You can find them here.
If you need help with your co-pay, or other financial assistance for your XALKORI prescription, programs are available for eligible patients (terms and conditions apply). Find the help you need here.
Understanding NSCLC and how XALKORI works may be a little easier with these helpful definitions.
Additional education and support for your fight
If you’d like to explore other resources to learn more about cancer care and how it’s changing, we recommend the following:
It's also a good idea to check with your hospital or cancer-care team for information about support groups near you.
XALKORI® (crizotinib) is a prescription medicine used to treat non-small cell lung cancer (NSCLC) that has spread to other parts of the body and is caused by a defect in a gene called ALK (anaplastic lymphoma kinase). It is not known if XALKORI is safe and effective in children.
Important Safety Information
XALKORI® (crizotinib) may cause serious side effects, some of which may include:
Liver problems — XALKORI may cause life-threatening or fatal liver injury. Your doctor should do blood tests to check your liver while you are taking XALKORI. Tell your doctor right away if you get any of the following:
- your skin or the whites of your eyes turn yellow
- you feel tired
- your urine turns dark or brown (tea color)
- you have nausea or vomiting
- you have a decreased appetite
- you have pain on the right side of your stomach
- you bleed or bruise more easily than normal
- you have itching
Lung problems (pneumonitis) — XALKORI may cause life-threatening or fatal swelling (inflammation) of the lungs during treatment. Symptoms may be similar to those symptoms from lung cancer. Tell your doctor right away if you have any new or worsening symptoms, including:
- trouble breathing or shortness of breath
- cough with or without mucous
Heart problems — XALKORI may cause very slow, very fast or abnormal heartbeats. Your doctor may check your heart during treatment with XALKORI. Tell your doctor right away if you feel dizzy or faint or have abnormal heartbeats. Tell your doctor if you take any heart or blood pressure medications.
Before you take XALKORI, tell your doctor if you:
- have heart problems, including a condition called long QT syndrome
- have liver or kidney problems
- have any other medical conditions
- are pregnant, or plan to become pregnant. XALKORI may harm your unborn baby.
- >Women who are able to become pregnant and men who take XALKORI should use birth control during treatment and for 3 months after stopping XALKORI.
- >Talk to your doctor about the birth control methods that may be right for you.
- >If you or your partner becomes pregnant, tell your doctor right away.
- are breastfeeding or plan to breastfeed. It is not known if XALKORI passes into your breast milk. You and your doctor should decide if you will take XALKORI or breastfeed. You should not do both.
Tell your doctor about the medicines you take, including prescription medicines, over-the-counter medicines, vitamins and herbal supplements.
Know the medicines you take. Keep a list of them to show your doctor or pharmacist when you get a new medicine.
You should not drink grapefruit juice or eat grapefruit during treatment with XALKORI. It may make the amount of XALKORI in your blood increase to a harmful level.
The most common side effects of XALKORI include:
- vision problems — these problems usually happen soon after starting XALKORI. Tell your doctor right away if you have any change in vision, such as double vision, flashes of light, blurred vision, light hurting your eyes, new or increased floaters.
- swelling of your hands or feet
- feeling tired
XALKORI may cause changes in your vision or make you feel tired or dizzy. If you have these symptoms avoid driving a car, using machinery or doing anything that needs you to be alert.
These are not all of the possible side effects of XALKORI. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088).
If you are uninsured or don’t have sufficient coverage for XALKORI, call 1-877-744-5675 to talk to a counselor at the Pfizer First Resource® Program. They are available Monday through Friday, 9 AM to 8 PM ET and can help verify whether you are eligible for patient assistance.
The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.
The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.